The Center for Networked Biomedical Research in Cancer (CIBERONC) (Spain), through the research group led by Xosé R. Bustelo, also belonging to the Cancer Research Center of Salamanca, has just discovered that the VAV1 gene, usually involved in the formation of a wide range of tumors, can also play roles involved in the suppression of some specific types of acute lymphoblastic leukemia of T lymphocytes.

This leukemia is the most frequent pediatric cancer and, even today, it poses many challenges for an adequate diagnosis and treatment. This discovery has just been published in the prestigious scientific journal Cancer Cell. T-lymphocytes are cells of the immune system whose function is to recognize and destroy cells from our organs that have become cancerous or that have been infected by viruses or other pathogens. They are also in charge of regulating other cells of the immune system, which are involved in the destruction of any external agent that invades our body, such as chemicals or bacteria. Despite these positive functions, T lymphocytes undergo in some cases genetic alterations that  turn them from protective agents to malignant cells that cause tumors.


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Posted by Juan M. Corchado

Juan Manuel Corchado (15 May 1971, Salamanca, Spain) is Professor at the University of Salamanca. He has been Vice-Rector for Research from 2013 to 2017 and Director of the Science Park of the University of Salamanca. Elected as Dean of the Faculty of Science twice, he holds a PhD in Computer Science from the University of Salamanca and a PhD in Artificial Intelligence from the University of the West of Scotland. He leads the renowned BISITE (Bioinformatics, Intelligent Systems and Educational Technology) Research Group, created in 2000. Director of the IoT Digital Innovation Hub and President of the AIR Institute, J. M. Corchado is also Visiting Professor at the Osaka Institute of Technology since January 2015, Visiting Professor at the Universiti Malaysia Kelantan and Member of the Advisory Group on Online Terrorist Propaganda of the European Counter Terrorism Centre (EUROPOL). J. M. Corchado has been president of the IEEE Systems, Man and Cybernetics Society, and academic coordinator of the University Institute for Research in Art and Animation Technology at the University of Salamanca, as well as researcher at the Universities of Paisley (UK), Vigo (Spain) and the Plymouth Marine Laboratory (UK). He currently combines all his activity with the direction of Master programmes in Security, Digital Animation, Mobile Telephony, Information Systems Management, Internet of Things, Social Media, 3D Design and Printing, Blockchain, Z System, Industry 4.0, Agile Project Management, and Smart Cities & Intelligent Buildings, at the University of Salamanca and his work as editor-in-chief of the journals ADCAIJ (Advances in Distributed Computing and Artificial Intelligence Journal), OJCST (Oriental Journal of Computer Science and Technology) or Electronics MDPI (Computer Science & Engineering section). J. M. Corchado mainly works on projects related to Artificial Intelligence, Machine Learning, Blockchain, IoT, Fog Computing, Edge Computing, Smart Cities, Smart Grids and Sentiment Analysis. He has recently been included in the board of trustees of the AstraZeneca Foundation, along with other health professionals and researchers recognised for bringing scientific knowledge closer to society.

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