A team of international experts has managed to identify various genes which are frequently altered in the lymphomas of the peripheral T-cells of an “unclear origin”.

This investigation relied on the collaboration of Professor Xosé Bustelo, from the Cancer Research Center and the scientific work has been published in the “Proceedings of the National Academy os Sciences os the United States” the official journal of the United States Science Academy. T-lymphocytes are blood cells in charge of destroying malignant cells which occasionally originate in the organs, as well as those that have been infected by viruses or other pathogens. They are also responsible of regulating other cells in the immune system which mediate the destruction of external agents that often invade the organism. Despite these positive roles, in some cases T-lymphocytes suffer genetic alterations in which they no longer are protector agents but malignant cells which cause tumors. One of the most frequent cancers that originates from these cells are the so called peripherals of T-lymphocytes.  These tumors have a high rate of 10 and 15 % out of all the tumors that originate from blood cells, they are characterized as highly malignant and aggressive. Without doubt, this is excellent news, since these researches could trigger the development of pharmaceutical treatments which are more effective in long-term cancer treatment.

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Posted by Juan M. Corchado

Vicerrector de Investigación y Transferencia - Universidad de Salamanca // Vice President for Research and Technology Transfer - University of Salamanca

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