This work has been published in the Proceedings of the National Academy of Sciences of the United States, the official journal of this Academy, and was carried out by a multi-centre group, including the laboratory of Dr. Xosé Bustelo of the Cancer Research Center (CIC-IBMCC) of Salamanca.

In a scientific article published this week, a multi-centre group with the participation of the laboratory of Dr. Xosé Bustelo of the Cancer Research Centre of Salamanca has reported the identification of several genes that are frequently altered in peripheral T-cell lymphomas of “unclear origin”. Among them is the proto-oncogene VAV1, which was found to be genetically altered (mutated) in 12% of the patients analysed. In the same study, alterations in this gene were also detected but with less frequency (3-7% of patients) in another related tumour, angioimmunoblastic T-cell lymphoma. Although it is epidemiologically less frequent, this tumour has malignant properties similar to those of peripheral T-cells.

News published in the media:

Posted by Juan M. Corchado

Catedrático en el Área de Ciencias de la Computación e Inteligencia Artificial de la Universidad de Salamanca. Director del Grupo de Investigación BISITE // Full Professor in Area of Computer Science and Artificial Intelligence at University of Salamanca. Director of the BISITE Research Group

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